Gene Shows Promise in Reducing Risk of Heart Diseases

Researchers from Cedars-Sinai Medical Center have been studying a plaque-fighting gene for the past 18 years. Lab mice, bred to model clogged arteries, were recently injected with the gene. The results, as announced by Cedars-Sinai, showed that the transfer helped reduce and stabilize plaque formation, as well as decreased inflammation- two main factors in reducing the risk of heart diseases.

The apolipoprotein A-I Milano gene was discovered in 1992 in a small number of Italians, and has been studied by P.K. Shah, M.D., the director of the Division of Cardiology and the Oppenheimer Atherosclerosis Research Center, ever since. He and his co-workers presented their findings in a presentation titled “Favorable Modulation of Atherosclerosis and Monocyte Phenotype by Intravenous AAV 8 Mediated Apo A-I Milano Gene Transfer in Mice”.

Cedars-Sinai Medical Center, where Adam Roseman is a member of the board, is an organization which works to provide high quality healthcare as well as to conduct state-of-the-art medical research.

Adam Roseman’s Work with Stars and Stripes

Every year the Stars and Stripes Fishing, Golf & Musical Festival holds a fundraiser. Its event this year raised over $1, 800, 000.  Among other charities, it will be giving money to the Big Brothers/Big Sisters of Orange County of which Adam Roseman is on the Board.  The organization itself has grown in leaps and bounds, considering its humble beginnings.  It began as “just a small fishing tournament looking to make a difference for kids,” said its founder Dick Gebhard, who founded Stars and Stripes in 1996. “The generosity of our community continues to astound me,” he added.   Indeed, what’s wonderful is how this event has now raised more than $11 million during its 14 year history.

Cedars-Sinai Sports Spectacular: Adam Roseman

May 23, 2010 saw the 25th Anniversary of the Cedars-Sinai Sports Spectacular.  This amazing event, heralded by the L.A. Times as the premier sports award dinner in the country, is a charity event established in 1986.  Since then, this event has raised over $19 million to benefit the Cedars-Sinai Medical Genetics Institute and its life-saving work.

While benefiting the important genetic research that the Institute undertakes, the event also benefits the Sports Spectacular Fellowship Endowment, which supports the training of five research Fellows at Cedars-Sinai Medical Center.

Many people have, over the years, served on the Steering Committee for this event including Adam Roseman, Erikk Aldridge, Dominique Alexander, Mike Altieri, Manuel Bergher and many others.  In the past, Adam Roseman has personally underwritten $50,000 for the event and has assisted with the benefit’s VIP after party.

Adam Roseman: Trust a Key Component of Investment Adviser’s Portfolio

from the Los Angeles Business Journal on the Web…
Trust a Key Component of Investment Adviser’s Portfolio
Special Report: Entrepreneurs in Their 20s
By HOWARD FINE Los Angeles Business Journal Staff

When local investment firm founder Adam Roseman walks into a room of potential investors or clients, he exudes such an air of maturity and mastery in the world of investing that people are “genuinely shocked” to realize that he’s under 30 years old.

At 29, Roseman has an impressive resumé: He joined local investment powerhouse Barrington Associates at just 23 years old and in less than three years built up a clientele sufficient enough that he was able to realize a lifelong dream of starting his own business.

Ten months later, in August 2005, Roseman opened the doors of ArcInvestment Partners, a private investment firm in the heart of Beverly Hills specializing in providing bridge financing to companies looking to go public. With funding from three wealthy families placed by their investment advisers, his firm now holds stakes totaling more than $10 million in various companies, and he has brought millions more in total financing to these companies.

But that’s not all. Roseman is an unusually active power player in the non-profit and political worlds. He’s the youngest board member at Cedars-Sinai Medical Center and the youngest board member of Big Brothers/Big Sisters Los Angeles. And he’s on the national finance committee for U.S. Senator and Democratic presidential candidate Hillary Clinton.

“I want to know that I make a difference,” Roseman said of his service on these boards and his political activism.

But his first loves are entrepreneurship and investing. He dreamed of being his own boss ever since he was a child growing up with a single mother, who is a substitute teacher.

Roseman started in the investment business at Lehman Bros. in San Francisco before deciding to move to Los Angeles to join Barrington. Even at that stage, he said he “wanted to learn finance enough, build a skill set and develop enough of a network to strike out on my own.”

When he finally decided to make his move, it was a bit scary. “The most challenging part was leaning on important relationships, convincing them to support me at such a young age in starting my own business.

“In my line of work, sometimes people initially don’t take me as seriously as they would someone older. That’s why I have to prove myself and establish credibility. And the only way you can do this is through performance.”

One of those he convinced was Ken Rickel, a principal in Liongate Capital, a private investment group. They met on a deal when Roseman was at Barrington and Rickel was immediately impressed. “He was young, but aggressive. He really knew what he was doing, way above what I was used to for a person that age.”
When Roseman went out on his own about a year later, “we decided to invest in him,” Rickel said.

Another company that ArcInvestment Partners has helped fund is Cyber Defender Corp., which supplies Internet security software for consumers. Chairman and Chief Executive Gary Guseinov said of Roseman: “He comes across as much older than what he actually is because he’s so accomplished. Most people are kind of shocked when they hear how old he is.” Guseinov said Cyber Defender is in the midst of attempting to go public and called the $4.5 million from ArcInvestment Partners a crucial step in that effort.